The Signal Journal
Back

Tag

precision-medicine

JAX Atlas Links 58 Genes to Type 2 Diabetes Beta Cells

The Jackson Laboratory published a single-cell genomic atlas of human pancreatic islets identifying 58 genes likely contributing to type 2 diabetes beta cell defects, including two previously unlinked genes, GRAMD2B and PDZK1. The atlas, drawn from nearly 250,000 cells across 48 donors, also documents a systematic

Nature Trial Backs Off-Label Cancer Treatment Effectiveness

A Nature-published genomics-guided trial finds off-label cancer treatments can be effective when matched to tumor genetic profiles. The findings could broaden prescribing options for patients beyond standard approved indications, pressing regulators and insurers to revisit reimbursement frameworks. The study appeared o

← Back

Tag

precision-medicine

Giant cancer study reveals effectiveness of ‘off label’ treatments

A Nature-published genomics-guided trial finds off-label cancer treatments can be effective when matched to tumor genetic profiles. The findings could broaden prescribing options for patients beyond standard approved indications, pressing regulators and insurers to revisit reimbursement frameworks. The study appeared o

2mo ago · 1 min · Technology

— End of feed —