Oxford University and the Serum Institute of India have agreed to jointly develop a new malaria vaccine called R78C. The Serum Institute, already the world's largest vaccine maker by volume, will handle manufacturing at scale once the candidate advances far enough to require it. The R78C vaccine is designed to target different stages of the malaria parasite, which sets it apart from earlier candidates that focus on a single stage. That multi-stage approach could make the vaccine more effective across a broader range of infections. Malaria kills hundreds of thousands of people each year, with sub-Saharan Africa bearing the heaviest burden. A more effective vaccine made at Serum's scale would directly affect how quickly and cheaply doses reach the populations most at risk. The Oxford-Serum pairing has prior form: their earlier collaboration produced the R21/Matrix-M malaria vaccine, which received WHO prequalification. Watch for early clinical data on R78C and any supply or pricing commitments tied to low-income country access.
Venezuela's earthquake death toll has reached 1,430 with the US Geological Survey warning fatalities could top 10,000, placing it among Latin America's deadliest in a century. US military planes are landing in Caracas, Washington is mobilising $150 million in aid, and rescue teams from 17 countries are on the ground.
Iranian armed forces attacked a cargo ship in the Strait of Hormuz on Thursday, briefly halting traffic through the waterway. The strike threatens a fragile US-Iran arrangement and could push shipping insurance costs and oil prices higher.
The US has struck Iran, with President Trump citing an Iranian attack on a ship in the Strait of Hormuz as justification. The action raises immediate risks for global oil flows through one of the world's most critical shipping chokepoints.
The US struck ten Iranian targets on the second consecutive day of military action, putting a fragile ceasefire under serious pressure. The escalation raises immediate risks for Gulf shipping, global oil supply, and regional stability.